From a process-equipment standpoint, permanent and single-use quaternary diaphragm pumps, such as Quattroflow™ pumps, represent a growing technology that both helps enable the efficient development of new biologic drugs and then facilitates the speed to market of the end-product. Single-use pumps, such as those using disposable pump chambers, feature replaceable wetted parts, meaning that no cleaning and validation process is needed during a product-development process that can require multiple trials. This white paper illustrates how one type of pump technology — positive displacement quaternary diaphragm — has become one of the preferred pumps to incorporate in critical biologics-handling applications.